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It can visualise individual atoms within materials. The STM ‘sees’ by measuring interactions between atoms, rather than by using light or electrons. Gerd Binnig and Heinrich Rohrer invent the scanning tunnelling microscope (STM). Thomas and Christoph Cremer develop the first practical confocal laser scanning microscope, which scans an object using a focused laser beam. 1978 – Confocal laser scanning microscope EBSP provide quantitative microstructural information about the crystallographic nature of metals, minerals, semiconductors and ceramics. John Venables and CJ Harland observe electron backscatter patterns (EBSP) in the scanning electron microscope. 1973 – Electron backscatter patterns observed With the help of a computer, the device combines many X-ray images to generate cross-sectional views as well as three-dimensional images of internal organs and structures. Godfrey Hounsfield and Allan Cormack develop the computerised axial tomography (CAT) scanner. GFP fluoresces bright green when exposed to blue light.
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Osamu Shimomura, Frank Johnson and Yo Saiga discover green fluorescent protein (GFP) in the jellyfish Aequorea victoria. 1962 – Green fluorescent protein (GFP) discovered Using a scanning point of light, confocal microscopy gives slightly higher resolution than conventional light microscopy and makes it easier to view ‘virtual slices’ through a thick specimen. Marvin Minsky patents the principle of confocal imaging. 1942 – Scanning electron microscopeĮrnst Ruska builds the first scanning electron microscope (SEM), which transmits a beam of electrons across the surface of a specimen. Here you’ll find several options for your timeline (we recommend Basic Timeline). In the 'Choose a SmartArt Graphic' gallery, select Process. By using interference rather than absorption of light, transparent samples, such as cells, can be imaged without having to use staining techniques. To begin creating your Word timeline, select Insert > SmartArt. Frits Zernike develops phase contrast illumination, which allows the imaging of transparent samples.